Great question! I've never seen Supernatural, but Star Trek is the first one that comes to mind for me, especially because of this:


The Three Amigos also occurred to me, but a lot of the jokes in that movie are about the guys being either stupid or spoiled, and a general audience might find that less sympathetic coming from women? A lot of people might think that from men it would be funny and from women it would annoying? Depressing, but that's my guess.

The Real Ghostbusters example is very interesting.